Thermostable vaccine against PPR disease

Reliable, Effective, and Accessible Disease Control for Small Ruminants.

The solution is a homologous live attenuated vaccine that effectively guards small ruminants against Peste des Petits Ruminants (PPR). The vaccine is proven to remain stable at ambient temperatures for extended periods, even withstanding spikes of 38°C for 9 days and 40°C for 7 days.

This technology is TAAT1 validated.

8•7

Scaling readiness: idea maturity 8/9; level of use 7/9

Project adoption1

Technology integrated in the ENSURE project.

See project details ›

IP

Open source / open access

Problem

Livestock mortality losses: PPR outbreaks can cause significant losses for farmers and livestock businesses through the death of sheep and goats.
Reduced production potential: Disease outbreaks can reduce the number of productive animals available for meat, breeding and other livestock activities.
Vaccination logistics costs: Maintaining cold storage and temperature controlled transportation can increase the cost of vaccine distribution.
Limited access to vaccination services: Producers in remote areas may face difficulties accessing vaccination campaigns when cold chain infrastructure is limited.
Risk of ineffective vaccine handling: Inadequate temperature control during storage or transportation can compromise vaccine stability.
Unpredictable business losses: PPR outbreaks can disrupt livestock production and create unexpected financial losses for producers.
Difficulty reaching dispersed herds: Livestock populations distributed across large areas can be difficult to vaccinate efficiently when vaccines depend on continuous cold chain management.
Need for reliable disease prevention: Livestock businesses require practical vaccination solutions that can maintain effectiveness under challenging field conditions.

Solution

Reduced livestock losses: Effective PPR vaccination helps protect sheep and goats against a disease associated with high mortality.
Lower cold chain requirements: Thermostability can reduce the logistical burden associated with maintaining continuous refrigeration during appropriate periods.
Improved access to vaccination: The technology facilitates vaccination in production areas where refrigeration facilities are limited.
Greater herd protection: Easier vaccine distribution can support the protection of larger numbers of animals.
Reduced disease related financial losses: Preventing PPR outbreaks can help producers protect their livestock assets and production income.
More flexible vaccine logistics: The vaccine's stability at elevated ambient temperatures facilitates transportation and handling under challenging field conditions.
Improved production continuity: Protecting animals from severe PPR outbreaks helps producers maintain more stable livestock production.
Reliable preventive health measure: The vaccine provides a practical disease prevention option that can complement broader livestock health management.

Key points to design your business plan

Using Disease Eradication through Thermotolerent PPR Vaccines technology significantly reduces the incidence of PPR outbreaks among small ruminants, thereby enhancing food security and improving livelihoods for farmers.

As essential collaborators, sellers of the product are indispensable. Regarding cost considerations, the vaccine dose typically ranges from 0.3 to 0.5 USD per animal.

Vaccination is recommended for all goats and sheep, irrespective of their production scale. A well-organized vaccinator can administer treatment to up to 5,000 animals monthly, ensuring a business with a satisfactory return on investment.

Animal owners are not obligated to obtain permits but are strongly encouraged or required to ensure all their animals receive treatment.

Adults 18 and over: Positive high

Others: No impact

The poor: Positive low

Under 18: Positive low

Women: Positive medium

Climate adaptability: Highly adaptable

Farmer climate change readiness: Significant improvement

Biodiversity: Positive impact on biodiversity

Environmental health: Moderately improves environmental health

Water use: Same amount of water used

Scaling Readiness describes how complete a technology's development is and its ability to be scaled. It produces a score that measures a technology's readiness along two axes: the level of maturity of the idea itself, and the level to which the technology has been used so far.

Each axis goes from 0 to 9 where 9 is the “ready-to-scale” status. For each technology profile in the e-catalogs we have documented the scaling readiness status from evidence given by the technology providers. The e-catalogs only showcase technologies for which the scaling readiness score is at least 8 for maturity of the idea and 7 for the level of use.

The graph below represents visually the scaling readiness status for this technology, you can see the label of each level by hovering your mouse cursor on the number.

Scaling readiness score of this technology

Maturity of the idea 8 out of 9

Uncontrolled environment: tested

Level of use 7 out of 9

Common use by projects NOT connected to technology provider

Maturity of the idea										Level of use
9
8
7
6
5
4
3
2
1
	1	2	3	4	5	6	7	8	9

Project	Countries	Beneficiaries	Budget (USD) & duration	Key figures
ENSURE Enabling Environments for Sustainable Regional Agriculture Extension	Kenya Rwanda Burundi Democratic Republic of the Congo South Sudan Uganda Tanzania	Direct: 3,000,000	13.14 million 2024–2027	149,940 farmers trained 9,996 Training 2→3.5 tons/ha cereals production expected 350 agent trained

Project

Countries

Beneficiaries

Budget (USD) & duration

Key figures

ENSURE
Enabling Environments for Sustainable Regional Agriculture Extension

Kenya
Rwanda
Burundi
Democratic Republic of the Congo
South Sudan
Uganda
Tanzania

Direct: 3,000,000

13.14 million

2024–2027

149,940 farmers trained
9,996 Training
2→3.5 tons/ha cereals production expected
350 agent trained

Figures in italic are from project plans and may change during implementation.

Countries with a green colour: Tested & adopted
Countries with a bright green colour: Adopted
Countries with a yellow colour: Tested
Countries with a blue colour: Testing ongoing

Countries where the technology is being tested or has been tested and adopted
Country	Testing ongoing	Tested	Adopted
Mali	–No ongoing testing	Tested	Adopted

This technology can be used in the colored agro-ecological zones. Any zones shown in white are not suitable for this technology.

Agro-ecological zones where this technology can be used
AEZ	Subtropic - warm	Subtropic - cool	Tropic - warm	Tropic - cool
Arid
Semiarid
Subhumid
Humid

Source: HarvestChoice/IFPRI 2009

The United Nations Sustainable Development Goals that are applicable to this technology.

Goal 1: no poverty

Goal 2: zero hunger

Goal 3: good health and well-being

Goal 8: decent work and economic growth

Goal 9: industry, innovation and infrastructure

Goal 12: responsible production and consumption

Goal 13: climate action

Report outbreaks of PPR to national veterinary authorities as PPR is a notifiable disease.
Implement disease surveillance considering animal movement, farm quarantine, and identification of high-risk areas.
Source vaccines from reliable suppliers and ensure proper cold chain management.
Administer vaccines through trained and certified vaccinators, ensuring correct dosage.
Monitor vaccinated animals for signs of immunity and address any concerns promptly.

Last updated on Oct 1, 2026